Getting to Midtown is easy. Once at the airport- take the Air Train to the Jamaica Station of the Long Island Rail Road- there are pletny of signs in the airport and peropl in red jackets and vests who can direct you. The air train is $5.00 per person and the ticket for the railroad is also seperate but check with customer service in the airtrain terminal, they may run package tickets. Take any train going to Penn Station- Once you are in Penn Station- take the 2 or the 3 (red line) subway one stop - uptown to 42nd street and you are in the middle- literally of Time Square. Should take you nore more than 35- 45 mins tops.
How to get to midtown from JFK