Danville, PA is off I-80, southwest of Scranton and northwest of Allentown. Check with Greyhound and others to see if they have a bus that stops there. Greyhound leaves from Port Authority Bus Terminal at 42nd St. & 8th Ave. You can get there from JFK by taking the NYAS bus which leaves from each terminal every 20 minutes ($15) or Airtrain from your terminal to Jamaica Station and transfer to the E subway to Port Authority ($7.25).
Danville, PA is off I-80,